Hendra Wibawa, Lestari, Toan Hong, Zaza Fahmia, Sri Handayani Irianingsih, Herdiyanto Mulyawan, Megaria Ardiani, Rochmadiyanto, Farida Camallia Zenal, Syafrison Idris, Gemma Clark

 

Abstract:

We reported the complete coding sequence of a Lumpy skin disease virus (LSDV) isolated from cattle in Central Java, Indonesia, in 2022. The nucleotide sequence of the virus was most closely related to LSDV strains belonging to clade 2.5, which has been reported in East and Southeast Asia from 2019 to 2021.

 

Conclusion:

The complete coding sequence of LSDV (LSDV/Semarang/A04224595/2022) was successfully obtained from skin nodules of cattle with LSD symptoms during the disease outbreak in Central Java Province in October 2022. The genome has 150,689 bp length with 25.9% GC content with the average sequencing depth was 139.9×. The genome was 99.99% identical (2–4 nucleic acid differences) to 4 LSDV strains detected in China, Taiwan, Vietnam, and Thailand between 2019 and 2021 and to 2 LSDV strains from the index case of LSDV in cattle in Riau Province, Indonesia in 2022 (Table 1). Our phylogenetic tree analysis showed that all the Indonesian LSD viruses are clustered in clade 2.5